SBME Virtual Seminar: John Edgar

SBME Virtual Seminar Series

(If you haven’t subscribed to our seminar notice list, email at least three hours prior to the start of the event for access. Please include your role and department/institution if applicable.)

Stem Cell-derived T-cells for Immunotherapy

Overview:Engineered T-cell therapies are being used clinically to treat cancers. Blood stem cells could provide an alternative source of engineered T-cells that reduces manufacturing costs and deliver a more potent therapeutic. This talk will focus on recent work to generate T-cells in vitro in a defined system that is amenable for clinical translation. It will discuss the use of quantitative modelling to predict changes in cytokine responses during differentiation of stem cells into T-cells, and how these models can be optimized to increase the yield and purity of generated T-cells.






John Edgar

PhD Student, Zandstra Lab  |  SBME









Jocelyn McKay

Research Officer  |  SBME