Associate Professor

 

Understanding the dynamics of biochemical networks is important for understanding life at the systems level and has practical implications for Medicine, Engineering, Biology, and Chemistry. The complex network of hemostasis consists of over 100 coupled reactions and has the death-defying function of regulating blood coagulation. Research in the Kastrup laboratory focuses on three problems related to blood coagulation: understanding the biophysical mechanisms by which blood clots form and degrade, controlling these processes to eliminate unwanted coagulation, and using coagulation as a scaffold for delivering therapeutics to diseased vasculature. This research lies at the interface of Chemical Biology, Bioengineering and Medicine. The techniques used include microfluidics, reconstituted protein systems, biomaterial synthesis, numerical simulations, and disease models of coagulation and atherosclerosis.

For more information about Dr. Kastrup’s research, please visit Google Scholar.